When we updated qmail a while ago, these became part of the default install. On boxes that had custom badmailfrom entries (it correpsonds to the /var/qmail/control/badmailfrom), the upgrade did not overwrite the file.
Those rules, in order mean
Don’t allow any e-mail addresses with spaces in them
Don’t allow any e-mail addresses that don’t look like X@X.X
Don’t allow any e-mail addresses with % in them
These entries aren’t critical - some open relay testers try to use some of those tricks to test for an open relay - and on old sendmail installs, they mighit work. But these rules block the attempts at the smtp level so the relay tester can’t say “might be an open relay!” even if it isn’t without those rules.
As for the reason InterWorx rejects them via the UI, that’s a bug.
So - you can keep them, or delete them, they aren’t critical.